Editorial process

How the calculator, the compound library and the guides are written, sourced, checked and kept current.

Every number on this site should be traceable: a calculator result back to the formula that produced it, and a figure on a compound page back to the study, label or database it came from. This page explains how we try to keep it that way. The methodology page covers the math itself.

Who writes the site

PeptidesCalculator.com is written and maintained by a small editorial team. We publish as a team rather than under individual bylines: a compound page is the product of research, drafting, source checking and a second read, not one person's opinion. The team is reachable at [email protected], and corrections are answered by a person.

We are not clinicians and we do not run studies. We read what regulators, journals, trial registries and chemistry databases have published, organize it, and show where each piece came from. Nothing on the site is medical advice, and no page is a prescribing guide.

Which sources we use

Compound pages and guides draw on four kinds of sources, and we link out to no others:

  • Regulators and governments. The FDA and its label repository DailyMed, the Federal Register, the NIH and its institutes, and their counterparts in other countries.
  • Peer-reviewed journals. Papers indexed in PubMed and PubMed Central, reached through the publisher or the DOI.
  • Trial registries. ClinicalTrials.gov and the equivalent national registries.
  • Chemistry and drug databases. PubChem for identity (CAS number, molecular formula, molar mass, sequence), and the maker's own label or filing for an approved medicine.

The build that publishes the site checks every outbound link against this policy. A page that links to a peptide seller, a dosing forum, another calculator or a personal site cannot be published: the build fails instead. Where a community figure is worth recording because it is what people actually report, it appears on the page as text, marked as community-reported, and is never linked.

How evidence is labeled

Each source on a compound page carries one of four labels, so a result in cells or mice is not mistaken for a finding in people:

  • Clinical: a study, trial or label concerning people.
  • Preclinical: animal, tissue or cell work.
  • Community-reported: amounts and schedules people report using, recorded for context and not as evidence of anything.
  • Database: identity and chemistry records such as PubChem.

From the balance of those sources each compound page carries an evidence tier in its header: Established human evidence (an approved medicine or a body of human trials), Human trials, Early human evidence, Preclinical-heavy (the human data is thin or absent) or Educational summary (sources are still being reviewed and no tier is assigned). Study summaries are tagged by study model (human, animal, in vitro, review) and never by a score of how well something works.

Reported amounts are presented as ranges recorded in the sources, with the starting, common and upper figures shown so a reader can recognize a number and sanity-check it. They are not recommendations. When a reader picks a compound in the calculator, the recorded example can be filled in as a starting point for the arithmetic, and every field stays editable.

How a page is checked

A new or revised compound page goes through the same steps before it is published:

  1. Identity. The compound's name, aliases, CAS number, formula and molar mass are checked against PubChem or the approved product's label, so a page is never about the wrong molecule or a blend mislabeled as a single compound.
  2. Sources. Each source is opened, its kind is labeled, and the year and publisher are recorded as they appear at the source.
  3. Figures. Every amount, duration and frequency on the page is traced to a specific source row. A figure we cannot trace is removed, not kept with a vague attribution.
  4. Regulatory status. Whether the compound is an approved medicine, is in trials, is restricted, or has no approved use, with the regulator's own page as the source.
  5. Plain language. The page is read for terms that are not explained, for claims that outrun the evidence, and for anything that reads like advice.
  6. Second read. A second member of the team reads the page against its sources before it goes live.

Calculator changes are held to a stricter standard than prose. The dosing arithmetic lives in small, pure functions, an automated test suite runs on every change, and the different calculator modes are tested against each other on the same inputs so they cannot drift apart. Every result on screen shows its working.

Dates and updates

Every compound page shows the date its sources were last reviewed, and every guide shows when it was published and when it was last reviewed. Those dates are the same ones we report to search engines in the page's structured data, so what a reader sees matches what a crawler is told.

A page is revised, and its date moved, when any of the following happens:

  • a regulator approves a product, changes a label, or issues a safety notice or import restriction;
  • a trial reports results or a new study changes what can be said about the evidence;
  • a reader points out an error or a better source;
  • the periodic review of the library reaches that compound.

Corrections

If you find an error, write to [email protected] with the page address and, if you have one, the source that shows the correct figure. We check it against the source, fix the page, and move its reviewed date. A correction that changes a number or a conclusion is noted on the page it concerns. We usually reply within one to two business days.

Software and AI tools

We use software, including AI tools, to help find and organize sources and to draft text. We do not publish anything that has not been checked by the team: every figure is traced to its source by a person, the evidence labels are set by a person, and the team is responsible for what appears on the site. The calculator's arithmetic is written and tested code, not a language model.

Funding and independence

Everything on the site is free and needs no account; an optional free account saves calculations to a workspace. The site is funded by advertising and by sponsored placements for research supplies, which are always labeled as sponsored. Sponsors do not see pages before they are published, do not choose which compounds are covered, and have no say in what a page says. We do not sell compounds, and the site does not link to compound sellers.

What the site is not

The site is an educational reference for research contexts. It is not medical advice, it does not replace a licensed professional, and it cannot verify your vial, your protocol or your situation. The about page says more about why the site exists, and the methodology page sets out every formula the calculator uses.