Pinealon (Bioregulator)

Pinealon Research and Aging

Research conducted in Russia suggests that Pinealon and a similar peptide called Vesugen may possess anti-aging properties, particularly in the central nervous system. These peptides have been found to have anabolic effects in the brain, potentially slowing the aging process when assessed using biological age indicators[^2^].

Pinealon’s influence extends beyond the central nervous system, as it also affects muscle cells by modulating the expression of irisin[^3^]. Irisin plays a crucial role in safeguarding muscle cells during exercise, promoting fat burning, and is believed to induce telomere elongation. By increasing the lifespan of irisin, Pinealon enhances telomere protection, combating the effects of aging and oxidative stress. Notably, plasma irisin levels are directly linked to telomere length in healthy adults. Furthermore, irisin levels have been associated with calorie restriction, a well-established method to prolong life and improve overall fitness[^4^]. These observations suggest that irisin, which Pinealon affects, may have systemic anti-aging effects throughout the body, including the brain.

Pinealon Research and Neuron Protection

Studies in prenatal rats indicate that Pinealon can protect neurons from oxidative stress, thereby preserving cognitive function and motor coordination[^5^]. These studies have demonstrated significant reductions in reactive oxygen species accumulation and the number of necrotic cells in the brains of prenatal rats treated with Pinealon. In essence, Pinealon helps safeguard neurons from cell death caused by oxidative stress.

The findings from the prenatal rat study have been substantiated and expanded upon in subsequent research. It has been confirmed that Pinealon offers protection against reactive oxygen species and reduces necrotic cell death. Additionally, it has been revealed that Pinealon modulates the cell cycle, primarily by activating proliferation pathways. In typical circumstances, this activation would lead to an increase in cell numbers. However, under conditions of oxidative stress, this effect counteracts some of the detrimental effects caused by reactive oxygen species[^6^]. This modulation at the DNA level suggests that Pinealon interacts with DNA, highlighting its potential therapeutic significance.

Please note that Pinealon’s application is primarily intended for educational and scientific research purposes and is restricted for sale to licensed researchers. It is not intended for human consumption.